UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to RELA

CUL1 — RELA

Pathways - manually collected, often from reviews:

Reactome Reaction: RELA → CUL1 (reaction) Suzuki et al., Biochem Biophys Res Commun 1999, Tan et al., Mol Cell 1999, Fuchs et al., Oncogene 1999, Wu et al., J Biol Chem 1999, Yaron et al., Nature 1998, Winston et al., Genes Dev 1999
Reactome Reaction: RELA → CUL1 (indirect_complex) Suzuki et al., Biochem Biophys Res Commun 1999, Tan et al., Mol Cell 1999, Fuchs et al., Oncogene 1999, Wu et al., J Biol Chem 1999, Yaron et al., Nature 1998, Winston et al., Genes Dev 1999

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Bind Interaction: Complex of 25 proteins Bouwmeester et al., Nat Cell Biol 2004
IRef Bind Interaction: Complex of 11 proteins Bouwmeester et al., Nat Cell Biol 2004
MIPS CORUM TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1): TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1) complex (ANKRD28-BTRC-CHUK-CUL1-IKBKE-NFKB2-PPP6C-REL-RELA-PPP6R1-PPP6R2-SKP1) Bouwmeester et al., Nat Cell Biol 2004
MIPS CORUM TNF-alpha/NF-kappa B signaling complex 5: TNF-alpha/NF-kappa B signaling complex 5 complex (CD3EAP-CHUK-CUL1-FBXW11-IKBKB-IKBKG-IQGAP2-KPNA2-LRPPRC-MCC-MTIF2-NFKB1-NFKB2-NFKBIB-PDCD2-POLR1A-POLR1B-POLR1D-POLR1E-POLR2H-POLR2L-RASAL2-REL-RELA-SKP1) Bouwmeester et al., Nat Cell Biol 2004
IRef Corum Interaction: Complex of 13 proteins (association, tandem affinity purification) Bouwmeester et al., Nat Cell Biol 2004
IRef Corum Interaction: Complex of 26 proteins (association, tandem affinity purification) Bouwmeester et al., Nat Cell Biol 2004
IRef Hprd Interaction: Complex of 170 proteins (in vivo) Bouwmeester et al., Nat Cell Biol 2004
IRef Hprd Interaction: Complex of 626 proteins (in vivo) Bouwmeester et al., Nat Cell Biol 2004

Text-mined interactions from Literome

Wong et al., Allergy 2006 : The induction of RANTES by SCF or TNF-alpha was mediated by ERK and NF-kappaB , respectively, and SCF induced MIP-1beta release was mediated by ERK
Singleton et al., Biochem Biophys Res Commun 2008 (Sepsis) : Glutamine attenuates inflammation and NF-kappaB activation via Cullin-1 deneddylation