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BMP10 — EPHB2
Text-mined interactions from Literome
Fan et al., J Cell Physiol 2006
(Cholestasis, Extrahepatic...) :
Furthermore,
BMP4 stimulated phosphorylation of Smad1 and
ERK1/2 in HSCs
Ghayor et al., Biochem Biophys Res Commun 2009
:
On the other hand,
BMP2 induced
Erk phosphorylation ( p44/p42 ) and cell proliferation were suppressed in the presence of cAMP
Jun et al., J Biol Chem 2010
:
Because
BMP signaling
induces Erk activation in osteoblasts, we sought to investigate whether BMP induced Erk signaling regulates Runx2 acetylation and stability
Takeda et al., Mol Cell Endocrinol 2012
(MAP Kinase Signaling System) :
Thus, the difference between BMP-6 and BMP-7 in enhancing GnRH induced FSHß transcription may be due to the differential
effects of
BMP ligands on GnRH induced
ERK signaling
Ge et al., J Bone Miner Res 2012
(MAP Kinase Signaling System) :
Significantly, in the presence of AA,
BMP2/7 synergistically stimulated RUNX2 S319 phosphorylation and transcriptional activity without affecting total RUNX2 and this response was totally
dependent on
ERK/MAPK activity ... Based on this work, we conclude that extracellular matrix and
BMP regulation of RUNX2 phosphorylation and transcriptional activity in osteoblasts is predominantly
mediated by
ERK rather than p38 MAPKs
Li et al., Cell stem cell 2012
:
Here, we show that, whereas LIF sustains relatively high ERK activity,
BMP4 can steadily
attenuate ERK activity by upregulating ERK-specific dual-specificity phosphatase 9 (DUSP9)
Li et al., Protein Cell 2012
:
We recently found that while LIF signaling augments ERK activity,
BMP signaling
inhibits ERK activity in mouse ES cells via direct upregulation of an ERK phosphatase-dual-specificity phosphatase 9