◀ Back to EPHB2
EPHB2 — HTR2C
Text-mined interactions from Literome
Werry et al., Biochem Pharmacol 2008
(MAP Kinase Signaling System) :
In conclusion, we provide evidence for remarkable flexibility in
5HT(2C)R mediated
ERK1/2 signaling that can be pharmacologically and mechanistically distinct depending on the agonist or edited isoform involved and on the duration of receptor activation
Li et al., Neurochem Int 2010
:
ERK ( 1/2 ) phosphorylation
induced by stimulation of either 5-HT(2B) or
5-HT(2C) receptors was mediated by epidermal growth factor (EGF) receptor transactivation ( Peng et al., this issue ), shown by the inhibitory effect of AG1478, an inhibitor of the EGF receptor tyrosine kinase, and GM6001, an inhibitor of Zn-dependent metalloproteinases, and thus of 5-HT(2B) receptor mediated EGF receptor agonist release