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PTH — SLC9A3R1

Text-mined interactions from Literome

Lederer et al., J Am Soc Nephrol 2003 : For studying the role of NHERF-1 on PTH regulation of these transporters, wild-type mNHERF-1 ( 1-355 ) or mNHERF-1 ( 1-325 ) lacking the ezrin binding domain were expressed in proximal tubule derived opossum kidney cells
Mahon et al., J Biol Chem 2004 (Calcium Signaling) : Actin is also an integral component of the NHERF-1 assembled complex because cytochalasin D disrupts apical localization of both NHERF-1 and the PTH1R and inhibits the PTH mediated increase of [ Ca2+ ] i. Expression of the first PDZ domain of NHERF-1 acts as a dominant negative interactor by blocking apical localization of the PTH1R and inhibiting PTH elicited increases of [ Ca2+ ] i
Friedman et al., Kidney Int Suppl 2004 (Bone Diseases) : Other provocative findings may provide a means of unifying determinations of PTH ( 7-84 ) with the effects of NHERF1 on PTH receptor signaling
Déliot et al., Am J Physiol Cell Physiol 2005 : Moreover, in mouse kidney slices, PTH induced an increase in NHERF1 phosphorylation ; independent activation of PKA or PKC also resulted in increased phosphorylation of NHERF1 in kidney slices
Sneddon et al., American journal of physiology. Renal physiology 2007 : EBP50 , a scaffolding protein that binds to the PDZ recognition domain of the PTH1R, impaired PTH but not isoproterenol or calcitonin induced ERK activation
Wheeler et al., Endocrine 2006 : Mutation of phenylalanine-34 of parathyroid hormone disrupts NHERF1 regulation of PTH type I receptor signaling
Wang et al., Mol Pharmacol 2009 : NHERF1 regulates parathyroid hormone receptor desensitization : interference with beta-arrestin binding
Wang et al., Bone 2013 : Parathyroid hormone (PTH) mediates actions on phosphate homeostasis mostly by regulating the activity of the type 2 sodium-phosphate cotransporter ( Npt2 ), and this action requires the PDZ protein NHERF1