Kis et al., Int J Cancer 2005
(Hodgkin Disease) :
LMP-1 could be induced by the histone deacetylase inhibitors TSA and n-butyrate, by 5-AzaC, a demethylating agent, and by phorbol ester
Chuang et al., Blood 2005
(Lymphohistiocytosis, Hemophagocytic) :
Interestingly, EBV LMP1 could transcriptionally inhibit the expression of SAP/SH2D1A and activate downstream molecules ERK and interferon-gamma (IFN-gamma)