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PPP1R12A — TNF

Text-mined interactions from Literome

Xing et al., Microvasc Res 2010 (Inflammation) : Both LPS and TNFalpha caused sustained activation of p38 and ERK1/2 MAP kinases, increased phosphorylation and degradation of negative regulator of NFkappaB signaling IkBalpha, and increased Rho-kinase mediated phosphorylation of myosin phosphatase MYPT1 leading to accumulation of phosphorylated myosin light chains
Arita et al., Invest Ophthalmol Vis Sci 2013 (Diabetic Angiopathies...) : TNF-a as well as DR sera promoted MYPT-1 phosphorylation in endothelial cells, which was significantly reduced by anti-TNF-a neutralizing antibody