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CASP12 — TXN

Text-mined interactions from Literome

Andoh et al., J Biol Chem 2003 : The activated PKG is required to protect cells from lipid peroxidation and apoptosis, to inhibit caspase-9 and caspase-3 activation, and to elevate the levels of Trx peroxidase-1 and Trx , which subsequently induces the expression of Bcl-2
Ramachandiran et al., Toxicological sciences : an official journal of the Society of Toxicology 2007 (Parkinsonian Disorders) : Divergent mechanisms of paraquat, MPP+, and rotenone toxicity : oxidation of thioredoxin and caspase-3 activation
Wang et al., Ann Neurol 2007 (Hypoxia-Ischemia, Brain) : Protection by NAC was associated with the following factors : ( 1 ) reduced isoprostane activation and nitrotyrosine formation ; ( 2 ) increased levels of the antioxidants glutathione, thioredoxin-2 , and ( 3 ) inhibition of caspase-3, calpain, and caspase-1 activation
Arai et al., Toxicol Appl Pharmacol 2008 : A role for TRX-1 expression on GSNO catabolism and cell viability was demonstrated by the concentration dependent effects of GSNO on decreasing TRX-1 expression, activation of caspase-3 , and increasing cell death ... The over-expression of TRX-1 in HeLa cells partially attenuated caspase-3 activation and enhanced cell viability upon GSNO treatment
Ueda et al., J Immunol 1998 (Necrosis) : Redox regulation of caspase-3 ( -like ) protease activity : regulatory roles of thioredoxin and cytochrome c