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CDS1 — MMP9
Text-mined interactions from Literome
Ha et al., Vascul Pharmacol 2004
:
In this study, we investigated the inhibitory
effect of
CDS on tumor necrosis factor-alpha (TNF-alpha) induced human aortic smooth muscle cells ( HASMC ) migration and
MMP-2 and -9 activity ... The results showed that
CDS inhibited
MMP-2 and -9 activity ( IC ( 50 ) =180 and 75 microg/ml, respectively )
Gao et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2012
(Pulmonary Disease, Chronic Obstructive) :
CDS could
increase the serum
MMP-9 level and the MMP-1 mRNA expression in the bone tissue, which might be one of reasons for the fact that cold and dry environment causes more bone resorption and bone degradation in COPD