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IFNG — NM

Text-mined interactions from Literome

Lemos et al., Proc Natl Acad Sci U S A 2009 (Arthritis, Rheumatoid...) : Methylated BSA ( mBSA ) and IL-23 induced neutrophil migration was inhibited by anti-IL-23 and anti-IL-17 antibodies, COX inhibitors, IL-12, or IFNgamma but was enhanced by prostaglandin E ( 2 ) ( PGE ( 2 ) ) ... IL-17 induced neutrophil migration was not affected by COX inhibitors, IL-12, or IFNgamma but was inhibited by MK886 ( a leukotriene synthesis inhibitor ), anti-TNFalpha, anti-CXCL1, and anti-CXCL5 antibodies and by repertaxin ( a CXCR1/2 antagonist ) ... Our results suggest that prostaglandin plays an important role in IL-23 induced neutrophil migration in arthritis by enhancing IL-17 synthesis and by inhibiting IL-12 and IFNgamma production
Ribeiro et al., Int J Exp Pathol 1990 : IFN-gamma induced neutrophil migration was enhanced when the macrophage population of the peritoneal cavities was increased by previous injection of thioglycollate and reduced by peritoneal lavage ... These results suggest that IFN-gamma induced neutrophil migration in vivo may be mediated by the release from resident macrophages of a neutrophil chemotactic factor and that dexamethasone blockade of neutrophil recruitment by IFN-gamma is due to inhibition of the release of this factor