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ESR1 — MMP13

Text-mined interactions from Literome

Potier et al., Am J Physiol Endocrinol Metab 2003 (Coronary Artery Disease...) : We examined and compared estrogen receptor ( ER ) and progesterone receptor (PR) expression and the effects of 17beta-estradiol ( E2 ) and progesterone ( P ) on collagen synthesis and matrix metalloproteinase ( MMP ) activities in the aortic arch and in cultured aortic smooth muscle cells ( ASMC ) of atherosclerosis-susceptible ( C57Bl6/J, B6 ) or -resistant ( C3H/HeJ, C3H ) mice
Lu et al., Biochim Biophys Acta 2006 : Using a rabbit synovial cell line lacking endogenous ER, a transient transfection system with an ER-alpha construct, and a series of MMP-13 promoter-luciferase constructs of varying lengths and with specific mutations in transcription factor binding sites, it was found that ER-alpha can significantly enhance MMP-13 promoter activity via the AP-1 site, with modulatory influences by the Runx and PEA-3 sites on this ER-alpha dependent enhancement of the promoter activity