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FGF2 — PTTG2
Text-mined interactions from Literome
Ishikawa et al., J Clin Endocrinol Metab 2001
(Neovascularization, Pathologic) :
As pituitary tumor transforming gene (
PTTG )
induces basic fibroblast growth factor (bFGF) , we tested angiogenesis induced by conditioned medium ( CM ) derived from NIH-3T3 transfectants overexpressing wild-type human PTTG ( WT-hPTTG-CM )
Horwitz et al., Mol Endocrinol 2003
(Pituitary Neoplasms) :
Pituitary tumor transforming gene (
PTTG ) originally isolated from GH-secreting pituitary adenoma cells causes in vitro cell transformation, in vivo tumorigenesis, and
induces basic fibroblast growth factor
McCabe et al., Clin Endocrinol (Oxf) 2003
(Adenoma...) :
Our data support a fundamental role for
PTTG mediated upregulation of
FGF-2 signalling in pituitary tumorigenesis and growth, and suggest that receptor mediated mechanisms of growth factor action may be critically important
Boelaert et al., FASEB J 2003
:
PTTG/securin transforms cells in vitro, inhibits sister chromatid separation, and
regulates secretion of
fibroblast growth factor-2 ... We propose a potential
role for human
PTTG/securin in modulating cell proliferation and
FGF-2 expression during human neurogenesis
Kim et al., Int J Gynecol Cancer 2008
(Endometrial Neoplasms) :
The pituitary tumor transforming gene (
PTTG ) is a novel oncogene expressed abundantly in most tumors,
regulates basic fibroblast growth factor secretion, and induces angiogenesis
Zhang et al., Mol Endocrinol 1999
(Cell Transformation, Neoplastic) :
Overexpression of
PTTG in transfected NIH 3T3 cells also
stimulated expression and secretion of basic
fibroblast growth factor , a human pituitary tumor growth regulating factor ... Overexpression of
PTTG in transfected NIH 3T3 cells also
stimulated expression and secretion of
basic fibroblast growth factor , a human pituitary tumor growth regulating factor