Gene interactions and pathways from curated databases and text-mining

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FGF2 — PTTG2

Text-mined interactions from Literome

Ishikawa et al., J Clin Endocrinol Metab 2001 (Neovascularization, Pathologic) : As pituitary tumor transforming gene ( PTTG ) induces basic fibroblast growth factor (bFGF) , we tested angiogenesis induced by conditioned medium ( CM ) derived from NIH-3T3 transfectants overexpressing wild-type human PTTG ( WT-hPTTG-CM )
Horwitz et al., Mol Endocrinol 2003 (Pituitary Neoplasms) : Pituitary tumor transforming gene ( PTTG ) originally isolated from GH-secreting pituitary adenoma cells causes in vitro cell transformation, in vivo tumorigenesis, and induces basic fibroblast growth factor
McCabe et al., Clin Endocrinol (Oxf) 2003 (Adenoma...) : Our data support a fundamental role for PTTG mediated upregulation of FGF-2 signalling in pituitary tumorigenesis and growth, and suggest that receptor mediated mechanisms of growth factor action may be critically important
Boelaert et al., FASEB J 2003 : PTTG/securin transforms cells in vitro, inhibits sister chromatid separation, and regulates secretion of fibroblast growth factor-2 ... We propose a potential role for human PTTG/securin in modulating cell proliferation and FGF-2 expression during human neurogenesis
Kim et al., Int J Gynecol Cancer 2008 (Endometrial Neoplasms) : The pituitary tumor transforming gene ( PTTG ) is a novel oncogene expressed abundantly in most tumors, regulates basic fibroblast growth factor secretion, and induces angiogenesis
Zhang et al., Mol Endocrinol 1999 (Cell Transformation, Neoplastic) : Overexpression of PTTG in transfected NIH 3T3 cells also stimulated expression and secretion of basic fibroblast growth factor , a human pituitary tumor growth regulating factor ... Overexpression of PTTG in transfected NIH 3T3 cells also stimulated expression and secretion of basic fibroblast growth factor , a human pituitary tumor growth regulating factor