Cecchinelli et al., Mol Cell Biol 2006
:
Gene-specific RNA interference demonstrates that HIPK2 is essential for repression of Gal-3 upon induction of p53 dependent apoptosis
Lavra et al., PloS one 2011
(Thyroid Neoplasms) :
Since we demonstrated that HIPK2 is involved in p53 mediated Gal-3 downregulation, we asked whether HIPK2 deficiency might be responsible for such paradoxical Gal-3 overexpression in WDTC