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CTNNB1 — GYS1

Text-mined interactions from Literome

Sakanaka et al., Recent Prog Horm Res 2000 (Neoplasms) : This regulation of cytosolic beta-catenin is mediated by glycogen synthase kinase-3 ( GSK-3 ) activity but in neither case is the mechanism known
Kaidanovich-Beilin et al., Biol Psychiatry 2004 (Disease Models, Animal) : Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus
Patel et al., Cancer Cell 2008 (Leukemia) : Dogma held that inhibition of the pleiotropic protein kinase glycogen synthase kinase-3 ( GSK-3 ) was procarcinogenic due to its natural repression of beta-catenin
Huang et al., J Mol Biol 2009 : Wnt3A, glycogen synthase kinase 3beta inhibitors or mutation of CSN mediated deneddylation induce the disassembly of the supercomplex and the accumulation of beta-catenin
Iseki et al., Cancer Sci 2010 : Interestingly, luciferase reporter analysis and quantitative real-time RT-PCR demonstrated that the ALEX1 promoter was up-regulated in a CRE dependent manner by continuous activation of Wnt/beta-catenin signaling induced by a glycogen synthase kinase-3 inhibitor and overexpression of beta-catenin
Torres et al., Mol Cell Biol 1999 : In developing embryos and in some human cancers, the accumulation of beta-catenin in the cytoplasm and subsequently the nuclei of cells may be regulated by the Wnt-1 signaling cascade and by glycogen synthase kinase 3 ( GSK-3 )