Gohda et al., J Immunol 2004
:
These results indicate that TRAF6 is essential for MyD88 dependent signaling but is not required for TIR domain containing adaptor inducing IFN-beta ( TRIF ) -dependent signaling
Yoshida et al., J Biol Chem 2008
(MAP Kinase Signaling System) :
Here, we demonstrate that TRAF6 is critical for IFN-alpha/beta induction in response to viral infection and intracellular double stranded RNA, poly ( I:C )