◀ Back to RUNX2
RBBP4 — RUNX2
Text-mined interactions from Literome
Kang et al., EMBO J 2005
:
Accordingly,
HDAC4 or 5 is
required for efficient TGF-beta mediated inhibition of
Runx2 function and is involved in osteoblast differentiation
Saito et al., Osteoarthritis Cartilage 2013
(MAP Kinase Signaling System) :
HDAC inhibitors ( TSA : 10nM, MS-275 : 100nM )
suppressed CTS induced expression of
RUNX-2 , ADAMTS-5, and MMP-3 at both the mRNA and protein levels within 1h ... The CTS induced expression of
RUNX-2 and ADAMTS-5 was
suppressed by
HDAC inhibitors via the inhibition of the MAPK pathway activation in human chondrocytes