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CAV1 — VCAM1
Text-mined interactions from Literome
Frank et al., Arterioscler Thromb Vasc Biol 2004
(Aortic Diseases...) :
Mechanistically, we demonstrated that loss of
Cav-1 resulted in the dramatic downregulation of certain proatherogenic molecules, namely, CD36 and
vascular cell adhesion molecule-1
Eum et al., Toxicol Appl Pharmacol 2009
:
In contrast, silencing of
caveolin-1 by siRNA interference did not
affect upregulation of ICAM-1 and
VCAM-1 in brain endothelial cells stimulated by PCB153
Han et al., Toxicol Appl Pharmacol 2010
:
Similarly, siRNA silencing of caveolin-1 in porcine endothelial cells confirmed the
caveolin-1 dependent
VCAM-1 expression ... These findings suggest that coplanar PCBs induce adhesion molecule expression, such as
VCAM-1 , in endothelial cells, and that this response is
regulated by
caveolin-1 and functional caveolae
Fernández-Hernando et al., Am J Pathol 2010
(Atherosclerosis) :
Mechanistically, overexpression of
Cav-1 reduced endothelial cell proliferation, migration, and nitric oxide production in vitro and
increased expression of
vascular cell adhesion molecule-1 in vivo