Gene interactions and pathways from curated databases and text-mining

◀ Back to EPHB2

EPHB2 — MAP3K11

Text-mined interactions from Literome

Chadee et al., Nat Cell Biol 2004 : MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation ... Our results define an unexpected role for MLK3 in mitogen regulation of B-Raf, ERK and cell proliferation
Chadee et al., Cell cycle (Georgetown, Tex.) 2004 : These results define a new role for MLK3 in B-Raf activation, ERK signaling and cell proliferation
Chadee et al., Proc Natl Acad Sci U S A 2006 : We show that the activation of ERK and the proliferation of human schwannoma cells bearing a loss-of-function mutation in the neurofibromatosis 2 (NF2) gene require MLK3 ... Thus, MLK3 is part of a multiprotein complex and is required for ERK activation
Hebron et al., Br J Haematol 2013 (Multiple Myeloma...) : In myeloma tumour cells, MAP3K8 acts as mitogen induced MAP3K in mitosis and is required for TNFa mediated ERK activation