◀ Back to IRF6

IRF6 — SLC17A5

Text-mined interactions from Literome

Deaciuc et al., Alcohol Clin Exp Res 2001 (Fatty Liver...) : LPS induced a significant increase in AST and the number of TUNEL positive nuclei, both effects being more pronounced in alcohol treated rats ... IDN1965 also abolished the increase in TUNEL positive nuclei, reversed the effect of LPS on plasma AST in alcohol treated rats, and prevented LPS induced necrosis
Saetre et al., Scand J Clin Lab Invest 2001 (Endotoxemia) : LPS caused significant increases in aspartate aminotransferase (AST) , alkaline phosphatase (ALP) and alpha glutathione S-transferase ( alpha-GST ), L-NAME caused further increases in AST, ALP and alpha-GST, while AE-ITU prevented the late increase in ALP and alpha-GST observed in the other LPS groups
Masaki et al., Hepatology 2004 (Drug-Induced Liver Injury...) : GalN/LPS treatment induced significant increases in aspartate aminotransferase (AST) and alanine aminotransferase ( ALT ) levels in the blood, apoptotic and necrotic changes in hepatocytes, and/or showed a high degree of lethality ... Pretreatment with adiponectin ameliorated the GalN/LPS induced elevation of serum AST and ALT levels and the apoptotic and necrotic changes in hepatocytes, resulting in a reduction in lethality
Guan et al., Arch Pharm Res 2005 (Liver Failure, Acute) : Ten of the synthesized chalcone derivatives exhibited inhibitory effects on D-GalN/LPS induced levels of AST and ALT in mice
Iida et al., Tohoku J Exp Med 2009 (Edema) : Bach1-deficiency suppressed induction of plasma alanine aminotransferase ( ALT ) and aspartate aminotransferase (AST) activities in response to the GalN/LPS-treatment
Wilhelm et al., Exp Mol Pathol 2009 (Drug-Induced Liver Injury...) : Compound a ( 25 and 50 mg/kg ; p.o. ) protected against the increase in aspartate aminotransferase (AST) activity induced by D-GalN/LPS
Abdel-Salam et al., Neurotox Res 2012 : LPS increased AST , ALT, and ALP in liver tissue by 84.4, 173.7, and 258.9 %, respectively
Jiang et al., J Ethnopharmacol 2013 : It revealed that LHR pretreatment effectively ameliorated the GalN/LPS induced elevation of serum ALT and AST levels, and attenuated hepatocyte apoptosis in the rat model characterized by the addition of GalN/LPS
Huang et al., Hepatology 1997 (Endotoxemia) : LPS increased the plasma levels of NO2- + NO3- and aspartate transaminase (AST) , and decreased the bile flow rate and hepatic adenosine triphosphate ( ATP ) level
Nishida et al., Gastroenterology 1998 (Necrosis) : LPS increased the plasma levels of aspartate aminotransferase (AST) and total bilirubin and decreased the hepatic adenosine triphosphate ( ATP ) level and bile flow rate ... LPS + BQ-485 infusion further increased the plasma levels of AST and total bilirubin and decreased the bile flow rate and the hepatic ATP level