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THPO — TYK2
Text-mined interactions from Literome
Ezumi et al., FEBS Lett 1995
:
Thrombopoietin , c-Mpl ligand,
induces tyrosine phosphorylation of
Tyk2 , JAK2, and STAT3, and enhances agonists induced aggregation in platelets in vitro
Oda et al., Blood 1996
:
To investigate the signaling processes induced by recombinant thrombopoietin, we used human platelets to recently show that
thrombopoietin induces rapid tyrosine phosphorylation of Jak2,
Tyk2 , Shc, Stat3, Stat5, and other proteins in human platelets
Miyakawa et al., Blood 1997
:
To investigate the signaling processes induced by thrombopoietin, we have employed human platelets and recently demonstrated that
thrombopoietin induces rapid tyrosine phosphorylation of Jak-2,
Tyk2 , Shc, Stat3, Stat5, p120 ( c-cbl ) and other proteins in human platelets
Sattler et al., J Cell Physiol 1997
:
We have previously shown that activation of c-MPL by
thrombopoietin rapidly
activates at least two cytoplasmic tyrosine kinases, JAK2 and
TYK2 , after ligand binding