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GNRH1 — IL6

Text-mined interactions from Literome

Russell et al., J Neuroendocrinol 2001 : We examined the effects of TNF-alpha and IL-6 on LHRH release from hypothalamic explants harvested from proestrus female and male rats in vitro
Yamaguchi et al., Horm Res 1991 : Interleukin-6 stimulates gonadotropin releasing hormone secretion from rat hypothalamic cells ... We established a primary culture system for hypothalamic neurons producing gonadotropin releasing hormone (GnRH) and examined whether IL-6 stimulated their GnRH secretion
Feleder et al., Biol Signals Recept 1998 : On the bases of previous papers indicating a stimulatory effect of IL-6 on LHRH release it could be considered that the potentiation of IL-6ra of the inhibitory effect of LPS on LHRH could be the consequence of the lack of the stimulatory effect of IL-6 on LHRH produced by the receptor antagonist ... This could confirm the stimulatory role of IL-6 on LHRH release