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NOTCH1 — PTGS2

Text-mined interactions from Literome

Bansal et al., PloS one 2009 : PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signaling ... Enforced expression of the cleaved Notch1 in macrophages induces the expression of COX-2 and MMP-9
Zhou et al., Dig Dis Sci 2013 (Carcinoma, Hepatocellular...) : Notch1 and Snail were down-regulated by RNA interference, and COX-2 was inhibited by NS-398 ... The down-regulation of Notch1 can also reduce the protein expression of COX-2