Marcar et al., Cancer Res 2010
(Bone Neoplasms...) :
Consistent with this idea, silencing of Mage-A expression leads to upregulation of several p53-responsive genes in a p53 dependent manner and stimulates by several fold the interaction of p53 with the p21 , MDM2, and PUMA promoters
Weeraratne et al., Neuro Oncol 2011
(Cerebellar Neoplasms...) :
This decrease in MAGE-A results in a concomitant increase in p53 and its associated transcriptional targets, p21/WAF1/CIP1 and, importantly, miR-34a