Johnson et al., J Biol Chem 2010
(Breast Neoplasms) :
Silencing p120 in ErbB2 dependent breast cancer cell lines dramatically inhibited migration and invasion as well as activation of Rac1 and Cdc42
Alcaide et al., Am J Physiol Cell Physiol 2012
:
Interestingly, overexpression of either p120-4A or p120-1A dramatically blocked TEM, and overexpression of p120-1A in HUVEC did not affect RhoA basal activity or activation of RhoA and Rac induced by thrombin or ICAM-1 crosslinking