Gene interactions and pathways from curated databases and text-mining

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GAST — IRF6

Text-mined interactions from Literome

Kim et al., Dig Dis Sci 2001 (Endotoxemia) : In addition, LPS enhanced gastric luminal fluid accumulation, decreased gastric mucosal blood flow ( laser Doppler ), and increased plasma gastrin levels ( radioimmunoassay ) ... Subdiaphragmatic truncal vagotomy, performed 7 days prior to LPS inhibited LPS induced fluid accumulation, further reduced gastric mucosal blood flow following LPS, and augmented LPS induced gastrin release compared to those in pyloroplasty controls ... Atropine ( 1 mg/kg i.p. ) prevented LPS induced fluid accumulation but did not influence the effects of LPS on blood flow or gastrin release
Liu et al., Br J Pharmacol 2001 : 5. Preincubation with TLCK, PDTC or infection with IkappaBalpha adenovirus abolished LPS stimulated GAS/GAF DNA binding
Brzozowski et al., J Pharmacol Exp Ther 2004 (Stomach Diseases) : Hp-LPS injected repeatedly suppressed the gastric acid secretion, up-regulated leptin mRNA and protein, and increased plasma leptin and gastrin levels