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NGF — POLDIP2
Text-mined interactions from Literome
Zaheer et al., Neurochem Res 2001
:
The inductions of BDNF and
NGF were also
blocked by inhibitors of
p38 and MEK, as well as by the inhibition of NF-kappaB with a decoy DNA sequence
Yung et al., Cell Signal 2008
(MAP Kinase Signaling System) :
NGF induced
p38 MAPK phosphorylation was abolished by inhibitors of Src ( PP1, PP2, and SU6656 ) and MEK1/2 ( U0126 )
Morillo et al., Mol Cell Biol 2012
(Nerve Degeneration) :
We demonstrate that the activation of p75 ( NTR ) by
nerve growth factor (NGF) induces nuclear
p38 ( MAPK ) kinase activity, which leads to Thr phosphorylation and subsequent recruitment of E2F4 to the E2F-responsive cdc2 promoter
Al-Gayyar et al., PloS one 2013
(Diabetes Mellitus, Experimental...) :
Inhibiting RhoA kinase with Y27632 significantly reduced diabetes- and
proNGF induced activation of proapoptotic
p38MAPK/JNK , expression of cleaved-PARP and caspase-3 and prevented retinal neurodegeneration in vivo and in vitro