Gene interactions and pathways from curated databases and text-mining

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NGF — POLDIP2

Text-mined interactions from Literome

Zaheer et al., Neurochem Res 2001 : The inductions of BDNF and NGF were also blocked by inhibitors of p38 and MEK, as well as by the inhibition of NF-kappaB with a decoy DNA sequence
Yung et al., Cell Signal 2008 (MAP Kinase Signaling System) : NGF induced p38 MAPK phosphorylation was abolished by inhibitors of Src ( PP1, PP2, and SU6656 ) and MEK1/2 ( U0126 )
Morillo et al., Mol Cell Biol 2012 (Nerve Degeneration) : We demonstrate that the activation of p75 ( NTR ) by nerve growth factor (NGF) induces nuclear p38 ( MAPK ) kinase activity, which leads to Thr phosphorylation and subsequent recruitment of E2F4 to the E2F-responsive cdc2 promoter
Al-Gayyar et al., PloS one 2013 (Diabetes Mellitus, Experimental...) : Inhibiting RhoA kinase with Y27632 significantly reduced diabetes- and proNGF induced activation of proapoptotic p38MAPK/JNK , expression of cleaved-PARP and caspase-3 and prevented retinal neurodegeneration in vivo and in vitro