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CA2 — FAS
Text-mined interactions from Literome
Rovere et al., J Immunol 1996
:
As intracellular Ca2+ release by inhibition of endoplasmic reticulum ATPases induces apoptosis in both recently and long term activated gamma delta cells, the molecular regulation of activation dependent apoptosis is likely to involve events upstream of
CD95 dependent
Ca2+ release
Kim et al., FASEB J 1996
(Body Weight...) :
Accordingly, we determined the
effect of
Ca2+ channel blockade ( nifedipine for 4 wk ) on
FAS and obesity in transgenic mice expressing the agouti gene in a ubiquitous manner
Esser et al., J Exp Med 1998
:
These results further define the
role of
Ca2+ in perforin and
FasL/Fas killing and demonstrate that differential Ca2+ signaling can modulate T cell effector functions