Gene interactions and pathways from curated databases and text-mining

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CCR7 — PTBP1

Text-mined interactions from Literome

Bhatt et al., J Immunol 2004 (Disease Models, Animal...) : We used traceable murine dendritic cells (DCs) and macrophage populations to chart their migratory pattern in response to Mtb, and found that only DCs receiving inflammatory stimuli from Mtb up-regulated their expression of CCR7 and migrated specifically to the draining lymph nodes ( LNs )
Tang et al., Blood 2004 (Neoplasms, Experimental) : Binding of the TAA/ecdCD40L protein to dendritic cells (DCs) resulted in the induction of CCR-7 chemokine receptor expression and cytokine release
Jang et al., J Immunol 2006 : In this study we report that LP-DCs in unperturbed mice require CCR7 to migrate to MLNs
Salazar-Gonzalez et al., Immunity 2006 (Salmonella Infections) : Thus, CCR6 dependent regulation of DCs is responsible for localized T cell dependent defense against entero-invasive pathogens
Dieu et al., J Exp Med 1998 : Finally, detection by in situ hybridization of MIP-3alpha mRNA only within inflamed epithelial crypts of tonsils, and of MIP-3beta mRNA specifically in T cell-rich areas, suggests a role for MIP-3alpha/CCR6 in recruitment of immature DCs at site of injury and for MIP-3beta/CCR7 in accumulation of antigen loaded mature DCs in T cell-rich areas