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EGF — JAK2

Text-mined interactions from Literome

Coaxum et al., Biochim Biophys Acta 2009 : In addition, EGF increased levels of tyrosine phosphorylation of Jak2 and CaM ... The EGFR kinase inhibitor, AG1478, blocked activation of NHE-1, but did not block EGF induced phosphorylation of Jak2 or CaM
Sayyah et al., Cell Signal 2011 : While the Y372F mutation had no effect on receptor independent, hydrogen peroxide mediated Jak2 activation, it impaired interferon-gamma ( IFN? ) and epidermal growth factor (EGF) dependent Jak2 activation
Akl et al., Planta Med 2012 (Breast Neoplasms...) : Western blot studies revealed that combined low-dose treatment of ?-tocotrienol and sesamin caused a marked reduction in EGF induced ErbB3 and ErbB4 receptors phosphorylation ( activation ) and a relatively large decrease in intracellular levels of total and/or phosphorylated c-Raf, MEK1/2, ERK1/2, PI3K, PDK1, Akt, p-NF?B, Jak1, Jak2 , and Stat1, as compared to cells treated with only one compound or in the vehicle treated control group
Zou et al., J Biol Chem 1997 : EGF dependent phosphorylation of E12R2, JAK2 , Tyk2, and STAT3 was observed