Gene interactions and pathways from curated databases and text-mining

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MTOR — PDGFB

Text-mined interactions from Literome

Yao et al., J Neurosci 2012 : Blocking TRPC1 channel suppressed PDGF mediated proliferation as well as PDGF-BB induced ERK/CREB and mTOR/4E-BP-p70S6K activation, thereby underscoring its role in this process
Razmara et al., Cell communication and signaling : CCS 2013 : Inhibition of phosphatidylinositol 3-kinase (PI3K) inhibited PDGF-BB activation of both mTORC1 and mTORC2 ... Inhibition of phosphatidylinositol 3-kinase (PI3K) inhibited PDGF-BB activation of both mTORC1 and mTORC2 ... In addition, PDGF-BB induced activation of mTORC1 , as measured by phosphorylation of the downstream S6 protein, was dependent on phospholipase D ( PLD )