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CTNNB1 — PPP2CA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Ratcliffe et al., J Biol Chem 2000
:
Although Wnt signaling is thought to occur via regulation of beta-catenin degradation,
PP2A-C did not significantly
affect beta-catenin stability
Zhang et al., J Biol Chem 2009
:
In this study, we show that
PP2A regulates
beta-catenin phosphorylation and degradation in vivo ... We demonstrate that
PP2A is
required for
Wnt/beta-catenin signaling in Drosophila
Hu et al., PloS one 2009
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
While exerting suppressive effects on BCR-ABL, E2F1, and
beta-catenin , IM/BOR and IM/PSI
inhibited proteasomal degradation of protein
phosphatase 2A (PP2A) , leading to a re-activation of this important negative regulator of BCR-ABL