Huang et al., Int Immunopharmacol 2010
:
It has been shown that GRb1 and PF inhibited the productions of IL-8 and PGE2 induced by capsaicin (CAP) in HaCaT cells and HEK 293T-TRPV1 cells ( which were transgenic and overexpressed TRPV1 ) but had no effect on HEK 293T mock cells ( p < 0.05 )
Lee et al., Phytother Res 2013
(Inflammation) :
GRb1 significantly reduced the upregulation of tumor necrosis factor-a, interleukin (IL)-1ß and IL-6 mRNA in the brain tissue at 4?h after LPS injection