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ARPC1B — RAC1
Text-mined interactions from Literome
Fucini et al., Mol Biol Cell 2002
:
Actin recruitment involves
Cdc42/Rac and
requires the activation of the
Arp2/3 complex
Olazabal et al., Curr Biol 2002
:
Rac and Cdc42 are
required for actin and
Arp2/3 complex recruitment during FcgammaR phagocytosis, while Rho controls actin assembly at CR phagosomes
Smith et al., Curr Biol 2004
:
WAVE/SCAR has long been known to activate the actin nucleating
Arp2/3 complex in a
Rac dependent manner
Shi et al., J Biol Chem 2005
:
The dramatic reorganization of the actin cytoskeleton required for internalization is driven by bacterial manipulation of host signaling pathways, including activation of the Rho family GTPase
Rac1 and subsequent
activation of the
Arp2/3 complex
Hall et al., Immunity 2006
:
In addition, a
Rac1/2 or Vav1/3 deficiency
blocks Arp2/3 recruitment and actin polymerization at the complement induced phagosome, indicating that these proteins regulate early steps in phagocytosis
Ten Klooster et al., Biochem J 2006
:
Interaction between Tiam1 and the
Arp2/3 complex links
activation of
Rac to actin polymerization