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CKS1BP7 — SKP1

Text-mined interactions from Literome

Sitry et al., J Biol Chem 2002 : Previous studies have shown that the cyclin dependent kinase (Cdk) inhibitor p27 ( Kip1 ) is targeted for degradation by an SCF ( Skp2 ) ubiquitin ligase complex and that this process requires Cks1 , a member of the highly conserved Suc1/Cks family of cell cycle regulatory proteins
Lin et al., Cell cycle (Georgetown, Tex.) 2006 : Importantly, our studies demonstrate that SCF ( xSkp2 ) supports the ubiquitination of Xic1 in a reconstituted in vitro ubiquitination assay and that this Xic1 ubiquitination does not require either CDK2-cyclins or Cks1
Yao et al., J Mol Biol 2006 : Activation of ubiquitin ligase SCF ( Skp2 ) by Cks1 : insights from hydrogen exchange mass spectrometry
Hoellein et al., Mol Cell Biol 2012 : Cks1 is an activator of the SCF ( Skp2 ) ubiquitin ligase complex that targets the cell cycle inhibitor p27 ( Kip1 ) for degradation