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APCS — IL12A

Text-mined interactions from Literome

Kodama et al., Jpn J Pharmacol 2002 (Neoplasms, Experimental) : In this study using BALB/c mice in which a Th-2 response is genetically dominant, D-fraction reduced the expression of Th-2 cytokine interleukin (IL)-4 but markedly increased the expression of Th-1 cytokine interferon (IFN)-gamma in CD4 ( + ) T cells and also increased IL-12p70 production as well as IFN-gamma production by antigen presenting cells (APCs), suggesting that D-fraction promotes the differentiation into Th-1 cells of CD4 ( + ) T cells through enhancement of IL-12p70 production by APCs
Uto et al., J Immunol 2007 (Listeriosis) : In vivo, gamma-PGA NPs were preferentially internalized by APCs ( DCs and macrophages ) and induced the production of IL-12p40 and IL-6
Maglione et al., J Immunol 2008 (Autoimmune Diseases...) : These data strongly suggest that FcgammaRIIB engagement can dampen the TB Th1 response by attenuating IL-12p40 production or activation of APCs
Horvat et al., J Immunol 2010 (Asthma...) : This phenotype was also characterized by increased pulmonary IL-12 and IL-17 expression and activation of APCs , as well as by reduced thymus- and activation regulated chemokine