Gene interactions and pathways from curated databases and text-mining

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CD38 — IRF1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Bauvois et al., J Interferon Cytokine Res 1999 (Leukemia, Hairy Cell) : This induction was independent of protein synthesis, suggesting that CD38 gene activation does not require IRF-1 but is merely under direct transcriptional regulation by latent IFN-inducible factors
Shen et al., Leukemia & lymphoma 2011 (Leukemia, Monocytic, Acute...) : Ectopic IRF-1 expression causes CD38 expression and activation of the Raf/MEK/ERK axis, and enhances RA-induced differentiation by augmenting CD38, CD11b, respiratory burst and G0 arrest