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Gopee et al., Cell Biol Toxicol 2004
:
The aim of current study was to investigate the effect of PKCalpha activation by FB1 on NF-kappaB activation and subsequently on TNFalpha gene expression and caspase 3 induction in LLC-PK1 cells
Zhang et al., Cancer Chemother Pharmacol 2005
(Melanoma, Experimental) :
These results indicate that quercetin induced apoptosis of murine melanoma B16-BL6 cells by injuring their mitochondria, increasing the activity of caspase-3 , inhibiting the expression of Bcl-2 and PKC-alpha , and inducing the translocation of PKC-delta
Chen et al., J Neurochem 2009
(MAP Kinase Signaling System) :
Simultaneous inhibition of PKCalpha and beta and MAPK abolished VP-induced Bad phosphorylation, but it only partially prevented caspase 3 inhibition