Gene interactions and pathways from curated databases and text-mining

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CSE — TNF

Text-mined interactions from Literome

Raza et al., FEMS Immunol Med Microbiol 1999 : Both RSV infection and CSE stimulated TNF-alpha release from monocytes and there was an additive effect if both the agents were present
Baginski et al., Am J Respir Cell Mol Biol 2006 (Carcinoma, Mucoepidermoid) : CSE also enhanced expression and production of MUC5AC mucin induced by epidermal growth factor receptor (EGFR) ligands TGF-alpha and amphiregulin, as well as LPS- and TNF-alpha- induced expression and/or release of TGF-alpha and amphiregulin
Zhang et al., Zhongguo Dang Dai Er Ke Za Zhi 2007 : Cigarette smoke extract (CSE) can induce injuries of pulmonary II epithelial cells, activate nuclear factor-kappaB and increase tumor necrosis factor-alpha(TNF-alpha) secretion
Mortaz et al., Respir Res 2009 : We observed that CSE augmented the production of IL-8 and suppressed the release of TNF-alpha , IL-6 and IFN-alpha
Jeong et al., Exp Dermatol 2010 : The aim of this study was to investigate the signalling of CSE induced Egr-1 expression and the role for Egr-1 in CSE induced TNF-alpha expression ... Involvement of Egr-1 in CSE induced TNF-alpha secretion was determined by using Egr-1 specific siRNA ... CSE increases TNF-alpha expression and secretion
Wu et al., J Ethnopharmacol 2011 : CSE dose-dependently inhibited the expression of pro-inflammatory cytokines IL-1ß and TNF-a in IL-1ß stimulated chondrocytes and LPS stimulated THP-1 macrophages
Yoon et al., The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2011 : This study investigated the effect of CSE on cell viability, migration, tumor necrosis factor (TNF)-a secretion, and contraction in normal human bronchial smooth muscle cells ( HBSMCs ) ... However, CSE had no effect on TNF-a secretion and NF-?B activation