Gene interactions and pathways from curated databases and text-mining

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HFE — TNF

Text-mined interactions from Literome

Distante et al., Scand J Gastroenterol 2003 (Hemochromatosis) : Our aim was to study the role of TNF-alpha and its promoter polymorphisms in the phenotypic expression of hemochromatosis in individuals with and without the C282Y mutation
Gordeuk et al., Blood 1992 (Hemochromatosis) : We conclude that release of TNF-alpha by monocytes may be selectively impaired in hereditary hemochromatosis
Candiracci et al., J Agric Food Chem 2012 : The results show that HFE significantly inhibited the release of pro-inflammatory cytokines such as TNF-a and IL-1ß