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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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LEP — SHBG

Text-mined interactions from Literome

Bełtowski et al., Life Sci 2006 (Body Weight...) : The effect of leptin ( 1 mg/kg i.p. ) on systolic blood pressure (SBP) was examined in lean rats and in rats made obese by feeding highly palatable diet for either 1 or 3 months ... In the 1-month obese group leptin had no effect on SBP , however, pressor effect of leptin was observed in animals pretreated with EDHF inhibitors ... In the 3-month obese group leptin alone increased SBP , and EDHF inhibitors did not augment its pressor effect
Nar et al., Gynecol Endocrinol 2009 : Although needing confirmation by a longer study, our findings suggest that IGF-I system and SHBG did not regulate leptin and vice versa and ERT do not have any effect on leptin, SHBG, and IGF-I
Vanbillemont et al., Clin Endocrinol (Oxf) 2012 : The association with fat mass could be mediated by the effects of adiponectin and/or leptin on SHBG synthesis
Geisthövel et al., Hum Reprod 1998 : Additional effects of endogenous C19-steroids, sex hormone binding globulin (SHBG) , luteinizing hormone ( LH ), follicle stimulating hormone ( FSH ), C-peptide and insulin on the predictive value of BMI on serum leptin were investigated in 56 hyperandrogenaemic and/or hyperinsulinaemic and/or obese premenopausal women