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IL12B — TGFB1

Text-mined interactions from Literome

Wilkinson et al., Scand J Immunol 2000 (Carcinoma...) : A regulatory role for interleukin (IL)-12 in production of transforming growth factor (TGF)-beta1 has been suggested, however, remains controversial ... In this study, we analyzed the effect of IL-12 on TGF-beta1 expression in the human lines, K562 and A549, and in primary human monocytes and macrophages
Tada et al., Eur J Immunol 2001 : Interestingly, TGF-beta1 enhanced IL-12 p40 production of anti-CD40/IFN-gamma stimulated LC, despite its down-regulatory effect on CD40 expression
Zhou et al., Nat Immunol 2007 : T helper cells that produce interleukin 17 ( IL-17 ; ` T ( H ) -17 cells ' ) are a distinct subset of proinflammatory cells whose in vivo function requires IL-23 but whose in vitro differentiation requires only IL-6 and transforming growth factor-beta ( TGF-beta )
Dey et al., Scand J Immunol 2007 (Leishmaniasis, Visceral) : These chemokines induced the known pro-inflammatory cytokine interleukin (IL)-12 secretion and inhibited the secretion of anti-inflammatory cytokines IL-10 and transforming growth factor-beta in infected macrophages
Zhao et al., J Huazhong Univ Sci Technolog Med Sci 2007 : Effect of TGF-beta1 on the expression of IL-12 , IL-15, IL-18, IL-4 and IL-10 in heart transplantation rejection in rats
de Beaucoudrey et al., J Exp Med 2008 (Genetic Diseases, Inborn) : We addressed the question of the development of human IL-17 -- producing T helper cells in vivo by quantifying the production and secretion of IL-17 by fresh T cells ex vivo, and by T cell blasts expanded in vitro from patients with particular genetic traits affecting transforming growth factor ( TGF ) beta , IL-1, IL-6, or IL-23 responses
Annunziato et al., Blood 2009 (Autoimmune Diseases) : While murine Th17 cells develop in response to IL-6, IL-1, and transforming growth factor ( TGF ) -beta , human Th17 cells originate from these CD161 ( + ) precursors in response to IL-1beta and IL-23 , the need for TGF-beta being controversial
Zhang et al., Clin Neurol Neurosurg 2010 (Autoimmune Diseases...) : IFNbeta inhibited IL-1beta, IL-23 and transforming growth factor ( TGF ) -beta ( which induce Th17 cell differentiation ), and induced IL-27, IL-12p35 and IL-10 ( which suppress it ) in dendritic cells (DCs) and B-cells
Ye et al., J Leukoc Biol 1995 : Furthermore, both transforming growth factor-beta and genistein, a tyrosine kinase inhibitor, could suppress IL-2 and IL-12 signaling but CsA was generally inactive
Fulton et al., J Infect Dis 1998 : Regulation of interleukin (IL)-12 production by coexpression of tumor necrosis factor (TNF)-alpha, IL-10, and transforming growth factor ( TGF ) -beta in human monocytes infected with Mycobacterium tuberculosis H37Ra was analyzed
Yasuda et al., J Clin Invest 1998 (Diabetes Mellitus, Type 1) : Reverse transcription-PCR analysis revealed that local production of IL-12p40 led to the decrease of interferon-gamma and the augmentation of transforming growth factor-beta at the graft site