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GPER1 — MAPK1

Text-mined interactions from Literome

Filardo et al., Mol Endocrinol 2000 (Breast Neoplasms) : In addition, GPR30 dependent Erk-1/-2 activation was triggered by ER antagonists, including ICI 182,780, yet not by 17alpha-estradiol or progesterone
Filardo et al., Mol Endocrinol 2002 (Breast Neoplasms...) : Transfection of GPR30 into MDA-MB-231 cells restores their ability to stimulate adenylyl cyclase and attenuate EGF induced activation of Erk-1/-2 by estrogen
Ahola et al., Eur J Biochem 2002 (Breast Neoplasms) : Thus we sought to establish whether different MAPK pathway inhibitors affect progestin induced GPR30 mRNA regulation
Ahola et al., Endocrinology 2002 (Breast Neoplasms) : Progestin and G protein coupled receptor 30 inhibit mitogen activated protein kinase activity in MCF-7 breast cancer cells ... Collectively, these results show that MAPK activity is inhibited by progestin and GPR30 and suggest that progestin induced ERK inactivation is mediated through GPR30
Fu et al., Gynecol Endocrinol 2007 : The aim of the present study was to explore the non-genomic activation of ERK1/2 mitogen activated protein kinase ( MAPK ) by 17beta-estradiol ( E ( 2 ) ) through mER and its role in cell proliferation