Gene interactions and pathways from curated databases and text-mining

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CALM3 — HTT

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Dudek et al., J Neuropathol Exp Neurol 2008 : Calmodulin (CaM) regulates TG2 cross linking of N-terminal mutant huntingtin in cells and colocalizes with TG and huntingtin in inclusions in Huntington disease cortex
Dudek et al., Brain Pathol 2010 : These data support the hypothesis that CaM regulates TG-catalyzed modifications of mutant huntingtin and that specific and selective disruption of the CaM-huntingtin interaction is potentially a new target for therapeutic intervention in HD