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CALM3 — HTT
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Dudek et al., J Neuropathol Exp Neurol 2008
:
Calmodulin (CaM) regulates TG2 cross linking of N-terminal mutant
huntingtin in cells and colocalizes with TG and huntingtin in inclusions in Huntington disease cortex
Dudek et al., Brain Pathol 2010
:
These data support the hypothesis that
CaM regulates TG-catalyzed modifications of mutant
huntingtin and that specific and selective disruption of the CaM-huntingtin interaction is potentially a new target for therapeutic intervention in HD