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CD55 — MAPK10
Text-mined interactions from Literome
Takeuchi et al., J Lab Clin Med 2001
:
The EGF induced
DAF expression was
inhibited by
mitogen activated protein ( MAP ) kinase kinase inhibitor PD 98059 but not by phosphatidylinositol-3 kinase inhibitor, phospholipase Cgamma inhibitor, or protein kinase C inhibitor
Mason et al., Am J Physiol Cell Physiol 2002
:
Investigation of mitogen activated kinase ( MAPK ) pathways also revealed differences, with bFGF induced
DAF dependent on p44/42 and p38
MAPK and VEGF requiring activation of p38 MAPK alone
Lidington et al., Am J Physiol Cell Physiol 2005
(MAP Kinase Signaling System) :
ERK1/2, p38, and JNK
MAPK were also
involved in thrombin induced
DAF upregulation, with evidence of interdependence between ERK1/2 and JNK
Nakdimon et al., PLoS Genet 2012
(Neoplasms) :
The insulin receptor
DAF-2 stimulates , while DAF-18 PTEN inhibits,
RAS/MAPK signaling in the vulval precursor cells ... Genetic and biochemical analyses indicate that
DAF-18 negatively
regulates vulval induction by inhibiting
MAPK activation
Komura et al., Biogerontology 2013
:
As skn-1 induces phase 2 detoxification enzymes, our findings suggest that cell wall components of bifidobacteria increase the average lifespan of C. elegans via activation of skn-1, regulated by the p38
MAPK pathway, but not by general
activation of the host defense system via
DAF-16