Gene interactions and pathways from curated databases and text-mining

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EPHB1 — EPHB2

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Cho et al., J Biol Chem 2003 : We reduced the level of caveolin-1 in senescent human diploid fibroblasts using its antisense oligonucleotides and small interfering RNA, and this resulted in the restoration of normal growth factor responses such as the increased phosphorylation of Erk , the nuclear translocation of p-Erk, and the subsequent activation of p-Elk upon epidermal growth factor stimulation
Vindis et al., J Cell Biol 2003 : Expression of dominant negative c-Src significantly reduced EphB1 dependent ERK1/2 activation and chemotaxis ... Together these findings highlight a new aspect of EphB1 signaling, whereby the concerted action of c-Src and p52Shc activates MAPK/ERK and regulates events involved in cell motility
Lee et al., Infect Immun 2005 : Our data indicate that the increased Ets/Elk and NF-kappaB promoter activities associated with M. smegmatis infected macrophages are responsible, at least in part, for the increased TNF-alpha and NOS2 production observed in these infected cells and that ERK1/2 is required for Ets/Elk activity and full TNF-alpha production
Vihanto et al., J Cell Sci 2006 : This interaction, as well as EphB1 mediated activation of extracellular-signal regulated kinase ( ERK ), was abrogated by overexpression of a caveolin-1 mutant lacking a functional scaffolding domain