Gene interactions and pathways from curated databases and text-mining

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ATP5O — NPPA

Text-mined interactions from Literome

Haverkamp et al., Vis Neurosci 1999 : It is possible that the gamma-ANP may be involved in regulating the activity of Na+/K+ ATPase or in the modulation of cGMP levels
Caruso-Neves et al., Biochim Biophys Acta 2004 : In the present paper we studied the effect of urodilatin and atrial natriuretic peptide (ANP) on the proximal tubule Na+-ATPase and ( Na+K+ ) ATPase activities ... Urodilatin and ANP inhibit the Na+-ATPase activity but not the ( Na+K+ ) ATPase activity
Fedorova et al., Hypertension 2006 : We studied effects of ANP on Na/K-ATPase phosphorylation and inhibition by an endogenous sodium pump ligand, marinobufagenin, in the aorta and renal medulla from male Sprague-Dawley rats ... Marinobufagenin ( 1 nmol/L ) inhibited Na/K-ATPase in aortic sarcolemma ( 18 % ) and in renal medulla ( 19 % ). prepro-ANP 104 to 123 ( ppANP ) and alpha-human ANP ( [ alpha-hANP ] both 1 nmol/L ) potentiated marinobufagenin induced Na/K-ATPase inhibition in the kidney, but reversed the effect of marinobufagenin in the aorta
Mills et al., Klin Wochenschr 1987 : Since ANP stimulates increased kallikrein release in rats and does not inhibit Na/K ATPase , it is suggested that the natriuretic pathway via inhibition of renal Na/K ATPase is independent in the kidney of the kallikrein/kinin natriuretic pathway
Zeidel et al., Clin Exp Pharmacol Physiol 1995 : Rather, ANP 31-67 inhibits basolateral Na/K-ATPase , probably via the stimulation of PGE2 synthesis