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IL1A — TGFB1

Text-mined interactions from Literome

Taki et al., Atherosclerosis 1999 (Arteriosclerosis) : IL-1 alpha , transforming growth factor-beta ( TGF beta ) and, to a lesser extent, tumor necrosis factor-alpha (TNF alpha) stimulated the IL-11 production by VSMC, and the stimulatory effects of IL-1 alpha and TGF beta on IL-11 production were dose dependent
Takahashi et al., J Pharmacol Exp Ther 1999 (Stomach Ulcer) : We investigated the role of endogenous interleukin (IL)-1 in the mRNA expression of cyclooxygenase (COX)-1, COX-2, inducible nitric oxide synthase (iNOS), cytokine induced neutrophil chemoattractant ( CINC ) -1, epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), hepatocyte growth factor (HGF), and transforming growth factor (TGF)-beta1 in acetic acid induced gastric ulcers in rats
Stefani et al., Pancreas 1999 (Liver Neoplasms...) : Both IL-1alpha and IL-1beta reduced CD44 membrane expression of MIA PaCa 2, while TGF-beta1 increased the percentage of CD44 positive CAPAN-1 cells
Loukinova et al., Int J Cancer 2001 (Carcinoma, Squamous Cell...) : TGF-beta1 suppressed constitutive as well as IL-1alpha and EGF-inducible Gro 1 production in both Pam 212 and LY-2 cells
Cheon et al., Clin Exp Immunol 2002 (Arthritis, Rheumatoid...) : Biological activity of IL-1 determined by mouse thymocyte proliferation assay was also enhanced by 50 % in response to TGF-beta1 in the culture supernatant of RA FLS
Shikhman et al., Am J Physiol Endocrinol Metab 2004 : Although both IL-1beta and TGF-beta1 enhance glucose transport in chondrocytes to a similar magnitude, IL-1beta induces significantly higher levels of lactate
Ashwood et al., Inflamm Res 2004 (Lymphoma) : We used the ELA4.NOB-1/CTLL co-culture IL-1 bioassay to investigate whether IL-1 activity was inhibited by IL-1ra and TGF-beta 1 in a predictable manner
Li et al., J Biol Chem 2006 : Surprisingly, this brief exposure to FC-AMs triggered a modest proinflammatory response in the phagocytes : tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL)-1beta were induced , whereas the levels of transforming growth factor-beta and IL-10 were not increased
Yao et al., J Biol Chem 2008 (Bone Resorption) : The bone matrix proteins dentin sialoprotein and osteopontin, but not transforming growth factor-beta , stimulated OCP expression of IL-1 and induced c-Fos expressing OCP differentiation into osteoclasts
Turner et al., Eur J Immunol 1991 : Transforming growth factor-beta 1 ( TGF-beta 1 ) mediates many immunosuppressive effects on immune cells and can inhibit the production of tumor necrosis factor and interleukin 1 (IL 1)
Chen et al., Zhong Xi Yi Jie He Xue Bao 2009 : Compared with the blank control group, IL-1beta might induce TEMT, which was showed in increasing expression of alpha-SMA, increasing secreting of FN and decreasing expression of E-cadherin, and at the same time the expressions of TGF-beta1 and ILK were enhanced ( P < 0.05 )
Nemunaitis et al., Eur J Haematol 1991 : Neither interleukin-1 (IL-1)beta nor IL-6 had an observable effect on TGF beta 1 mRNA expression
Nowinski et al., J Cell Biochem 2010 : Human dermal fibroblasts and NIH 3T3 cells were treated with IL-1alpha or beta in presence or absence of TGF-beta1
Turner et al., Cytokine 1990 : Furthermore, when a panel of stimuli were compared for their ability to induce IL 1 , TNF and IL 6 in the presence or absence of TGF beta 1 , IL 6 levels were augmented in the presence of TGF beta 1, while the induction of IL 1 and TNF was inhibited significantly
Bristol et al., J Immunol 1990 : IL-1 alpha induces expression of active transforming growth factor-beta in nonproliferating T cells via a post-transcriptional mechanism
Brennan et al., Clin Exp Immunol 1990 (Arthritis, Rheumatoid) : This was confirmed by the observation that neither TGF-beta 1 or TGF-beta 2 inhibited spontaneous IL-1 or TNF-alpha production by rheumatoid synovial mononuclear cells in culture
Wei et al., Spine (Phila Pa 1976) 2013 : Gene expression of ADAMTS-4, ADAMTS-5, and TGF-b were not affected by IL-1 or ERK inhibition
Reinhold et al., Cytokine 1994 : In this study we have analysed in parallel the effects of TGF-beta 1 on both DNA synthesis and production of the cytokines IL-1 , IL-2, IL-6, and TNF-alpha by pokeweed mitogen stimulated peripheral blood mononuclear cells
Gautam et al., Oncol Res 1993 (Astrocytoma) : Interferon gamma (IFN gamma), transforming growth factor beta 1 ( TGF-beta 1 ), granulocyte-macrophage colony stimulating factor ( GM-CSF ) and granulocyte-colony stimulating factor ( G-CSF ) did not induce IL6 mRNA production ; however, IL6 mRNA expression and protein production was strongly induced by IL1 alpha and to a lesser extent by IFN alpha
Barnum et al., J Immunol 1994 (Inflammation) : In this report, we show that transforming growth factor-beta ( TGF-beta ) can significantly inhibit the capacity of IFN-gamma, IL-1 beta, and TNF-alpha to augment expression of the central component of complement C3 in the human astroglioma cell line D54-MG. Treatment of D54-MG cells with TGF-beta alone had no dose- or time dependent effect on basal C3 protein or mRNA levels
Villiger et al., J Immunol 1993 : However, IL-1 inhibited TGF-beta 1 mRNA expression induced by serum
da Cunha et al., J Neuroimmunol 1993 : IL-1 alpha stimulated TGF-beta 1 production in all glial cell types, whereas IL-1 beta did not ... These results indicate that TGF-beta 1 may be induced by IL-1 in all glial cells of the frontal cortex, by both autocrine and paracrine mechanisms
Danforth et al., Cancer Res 1993 (Breast Neoplasms) : IL-1 , but not IL-6, increased secretion of transforming growth factor-beta ( TGF-beta ) by 2.45-fold over 72 h ( P < 0.01 )
Kitamura et al., Kidney Int 1995 : Transfer of a mutated gene encoding active transforming growth factor-beta 1 suppresses mitogenesis and IL-1 response in the glomerulus ... These data indicate that TGF-beta 1 inhibits mitogenesis and IL-1 response of the glomerulus and may, in part, act as a potential early suppressor of glomerular inflammation
Fischer et al., Ann Oncol 1995 (Carcinoma, Non-Small-Cell Lung...) : Furthermore, TGF beta 1 suppressed secretion of IL-2, IFN alpha, IFN gamma, TNF alpha but not of IL-1 alpha and IL-1 beta in whole blood cell cultures from healthy individuals
Kumar et al., J Cell Physiol 1996 : In the current study, we sought to investigate whether TGF beta 1 induced the expression of IL-1 alpha and IL-8 in rat alveolar epithelial cells ... These results suggest that TGF beta 1 may regulate IL-1 alpha and IL-8 expression in alveolar epithelial cells and contribute to polymorphonuclear leukocyte recruitment and lung injury in clinical states with increased TGF beta 1
Kang et al., Exp Dermatol 1996 : Differential regulation of IL-1 and IL-1 receptor antagonist in HaCaT keratinocytes by tumor necrosis factor-alpha and transforming growth factor-beta 1
Colasante et al., Am J Respir Crit Care Med 1997 (Adenocarcinoma...) : TGF beta 1 and IL-8 production and their regulation by IL-1 in five non-small-cell ( NSC ) lung tumor cell lines were evaluated
Kim et al., Pharmazie 1998 : Neither GDF-5 nor TGF-beta 1 had a significant effect on IL-1 alpha production in keratinocyte monolayer cultures