Gene interactions and pathways from curated databases and text-mining

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GH1 — IRS1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Duan et al., J Biol Chem 2004 : Similarly, SH2-B promoted growth hormone stimulated tyrosine phosphorylation of IRS1 in both HEK293 and MEF cells
Souza et al., J Biol Chem 1994 : Growth hormone stimulates tyrosine phosphorylation of insulin receptor substrate-1
Argetsinger et al., J Biol Chem 1995 : Growth hormone , interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1
Ridderstråle et al., J Biol Chem 1995 : Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes
Chow et al., Endocrinology 1996 : Growth hormone stimulates tyrosine phosphorylation of JAK2 and STAT5, but not insulin receptor substrate-1 or SHC proteins in liver and skeletal muscle of normal rats in vivo
Yamauchi et al., J Biol Chem 1998 : Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1 , -2, and -3, their association with p85 phosphatidylinositol 3-kinase ( PI3-kinase ), and concomitantly PI3-kinase activation via JAK2 kinase