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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to ICAM1

FGF2 — ICAM1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: ICAM1 → FGF2 (decreases)
    Evidence: The cells treated by 10 ng/ml of bFGF, showed the significant decrease in basal ICAM-1 expression. The expression reduced from 400 units to 100 units.

Text-mined interactions from Literome

Kikuchi et al., Nihon Rinsho Meneki Gakkai Kaishi 2000 : The expression of ICAM-1 and E-selectin induced by TNF-alpha was not inhibited by either bFGF or VEGF
Zhang et al., J Leukoc Biol 2001 : Stimulation of human umbilical vein endothelial cells by VEGF or bFGF for 18 h up-regulated intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 expression and significantly increased PMNL adhesion and TEM in response to complement fragment 5a ( C5a ) or interleukin (IL)-8
Nakano et al., Arthritis Rheum 2004 (Arthritis, Rheumatoid...) : FGF-2 induced the expression of both RANKL and ICAM-1 on RASFs more so than on OA synovial fibroblasts ( OASFs ) ... FGF-2 induced up-regulation of RANKL and ICAM-1 was inhibited by anti-FGF-2 antibody
Bouma-ter Steege et al., Clin Cancer Res 2004 (Breast Neoplasms...) : In vitro, both VEGF-C and VEGF-D were found to decrease endothelial ICAM-1 expression in the presence of basic fibroblast growth factor
Lichtenstein et al., Neurosignals 2012 (MAP Kinase Signaling System) : We report that FGF2 induced the upregulation of monocyte chemoattractant protein ( CCL2 ) and cyclo-oxygenase type 2 (COX2), and the inhibition of lipopolysaccharide elicited ICAM1 upregulation
Griffioen et al., Int J Cancer 1999 (Neovascularization, Pathologic) : Here, we present data to show that the angiogenesis inhibitor platelet factor-4 (PF4) is able to prevent basic fibroblast growth factor (bFGF) induced down-regulation of intercellular adhesion molecule-1 ( ICAM-1 ) ... Furthermore, PF4 restores ICAM-1 expression following bFGF induced down-regulation of ICAM-1