Hagemann et al., J Immunol 2005
(Breast Neoplasms...) :
EMMPRIN and MIF were up-regulated in cocultured tumor cells in a JNK- and NF-kappaB dependent manner
Kim et al., Immune network 2009
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Stimulation of CD147 with its specific monoclonal antibody induced the expression of matrix metalloproteinase (MMP)-9 in THP-1 cells and it was suppressed by inhibitors of both ERK and NF-kappaB Venkatesan et al., J Mol Cell Cardiol 2010
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We show for the first time that EMMPRIN stimulates the activation of NF-kappaB , AP-1, CREB, and ATF-2 in cardiomyocytes, and induces IL-18 expression via Rac1 dependent PI3K/Akt/IKK/NF-kappaB and MKK7/JNK/AP-1 signaling