Gene interactions and pathways from curated databases and text-mining

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IL2 — TYR

Text-mined interactions from Literome

Delespine-Carmagnat et al., Eur J Immunol 2000 : These experiments provide direct biochemical evidence that binding to the IL-2R of the adaptor protein Shc requires phosphorylation of Tyr-338 in the IL-2Rbeta acidic subdomain
Kim et al., Biochem Biophys Res Commun 2009 : Hph-1-ZAP-70-Y319F inhibited the phosphorylation of ZAP-70-Tyr319, LAT-Tyr191 , and p44/42 MAPK induced by TcR stimulation, NFAT- and AP-1 mediated gene transcription, and the induction of CD69 expression and IL-2 secretion
Chi et al., Brain Res Bull 1989 : Tyr-MIF-1 did not activate PBL to produce IL 2 nor did it affect the production of IL 2 by Con A-stimulated PBL ... The results suggest that Tyr-MIF-1 does not directly modulate CD 2, CD 4 and CD 8 expression, does not alter the proliferative response of PBL, and does not affect the production of IL 2